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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T13253 | Umibecestat | CNP520 | BACE |
Umibecestat is an inhibitor of beta-site amyloid precursor protein cleaving enzyme-1 (BACE-1), with IC50s of 11 nM and 10 nM for human BACE-1 and mouse BACE-1, respectively. Umibecestat can be used for the research of al... | |||
T24924 | Umibecestat HCl (1387560-01-1 free base) | CNP 520,Umibecestat HCl,Umibecestat hydrochloride,CNP520,CNP-520 | |
Umibecestat is a beta-secretase inhibitor. CNP520 has a selectivity, pharmacodynamics, and distribution profile suitable for AD prevention studies. | |||
T69663 | G108 | ||
G108 is a Novel h-cGAS specific inhibitor for repression of dsDNA-triggered interferon expression (IC50 of 27.5 nM and 5150 nM for h-cGAS and m-cGAS, respectively). | |||
T69664 | Umibecestat HCl | ||
Umibecestat, also known as CNP-520, is a beta-secretase inhibitor and is a drug candidate for prevention trials in Alzheimer's disease. CNP520 has a selectivity, pharmacodynamics, and distribution profile suitable for AD... |